IN DIALOGUE WITH MORE-THAN-HUMAN WOR(L)DS: COLLABORATIVE KINSHIP AND RELATIONALITY IN DIGITAL PUBLISHING




Dynamic conformations of the P. furiosus MR-DNA complex link Mre11 nuclease activity to DNA-stimulated Rad50 ATP hydrolysis

Abstract The MRE11-RAD50-NBS1/Xrs2 (MRN/X) protein complex has essential roles in the repair of damaged DNA.The current understanding of the conformational landscape of the core MR complex comes from various structural studies.However, Prep given the heterogeneous nature of these structures, we suspect that several conformational states may still b

read more